I really think Off-label prescribing in common and it commonly prevalent worldwide. It gives the freedom to physicians to apply new therapeutic options based on the latest evidence . Off-label prescribing can helps in treating some serious conditions as well. Off- label prescribing helps in treating diseases or medical condition that is not approved to treat but it can be beneficial for some patients . Off- labelling can helps other physicians to apply their knowledge and treat various kinds of diseases. Off- labels drugs uses can become widely entrenched in clinical practice and becomes predominant treatments for a given clinical conditions . It can be beneficial when the patients have exhausted all the approved options to cure any sort disease and conditions and it be safe if it is taken in prescribed amount . Some